H-2Kd/H-2Dd antibody (Biotin)

Catalog No. ABIN135418

This Mouse Monoclonal antibody specifically detects H-2Kd/H-2Dd in FACS, ICC, IP and IEM. It exhibits reactivity toward Mouse. It has been mentioned in 3+ publications

Quick Overview for H-2Kd/H-2Dd antibody (Biotin) (ABIN135418)

Target: H-2Kd/H-2Dd

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: Biotin

Application: Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunoprecipitation (IP), Immunoelectron Microscopy (IEM)

Clone: 34-1-2S

Product Details

Purpose: Mouse Anti-Mouse H-2Kd/H-2Dd-BIOT

Specificity: Mouse H-2Kd/H-2Dd

Characteristics: Biotin Anti-Mouse H-2Kd/H-2Dd antibody for use in flow cytometry, immunocytochemistry, electron microscopy, and immunoprecipitation assays.

Immunogen: BDF1 mouse splenocytes

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Phosphate buffered saline containing < 0.1 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2-8°C

References

Abel, Goto, Magnuson, Abraham, Ramanathan, Hotaling, Alaniz, Kumar-Sinha, Dziubinski, Urs, Wang, Shi, Waghray, Ljungman, Crawford, Simeone: "HNF1A is a novel oncogene that regulates human pancreatic cancer stem cell properties." in: eLife, Vol. 7, (2019) (PubMed).

Pal, Dziubinski, Di Magliano, Simeone, Owens, Thomas, Peterson, Potu, Talpaz, Donato: "Usp9x Promotes Survival in Human Pancreatic Cancer and Its Inhibition Suppresses Pancreatic Ductal Adenocarcinoma In Vivo Tumor Growth." in: Neoplasia (New York, N.Y.), Vol. 20, Issue 2, pp. 152-164, (2018) (PubMed).

Chen, Fisher, Signs, Molina, Shenoy, Lopez, Baker, Koomen, Chen, Gittleman, Barnholtz-Sloan, Berg, Appelman, Huang: "Inhibition of PI3K/Akt/mTOR signaling in PI3KR2-overexpressing colon cancer stem cells reduces tumor growth due to apoptosis." in: Oncotarget, Vol. 8, Issue 31, pp. 50476-50488, (2017) (PubMed).

Target Details

Target: H-2Kd/H-2Dd

Background:

Description: Mouse Anti-Mouse H-2Kd/H-2Dd-BIOT

NCBI_Official_Symbol: H2-K1, H2-D1

Synoynms: MHC Class I

Gene ID: 14972

UniProt: P01902