Histone 3 antibody (AA 26-30)

Catalog No. ABIN1355846

There are 3+ publications for this product available. The Rabbit Polyclonal anti-Histone 3 antibody is suitable to detect Histone 3 in samples from Human, Mouse and Rat. It has been validated for WB.

Quick Overview for Histone 3 antibody (AA 26-30) (ABIN1355846)

Target: Histone 3 (H3) (Histone H3 (H3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Histone 3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Histone 3 Antibody

Binding Specificity: AA 26-30

Specificity: The antibody detects endogenous level of total Histone H3 protein.

Immunogen: Peptide sequence around AA 26-30 (A-R-K-S-A) derived from Human Histone H3. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Application Details

Application Notes: Western blotting: 1:500-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C

References for anti-Histone 3 antibody (ABIN1355846)

Zhang, Zhou, Huang, Bi, Zhou: "Paeoniflorin reduced BLP-induced inflammatory response by inhibiting the NF-?B signal transduction in pathway THP-1 cells." in: Central-European journal of immunology / Polish Society for Immunology and eleven other Central-European immunological societies, Vol. 39, Issue 4, pp. 461-7, (2015) (PubMed).

Sun, Zhao, Zhang, Qu, Wang, Xue, Li, Mu, Lu: "Protective effects of Salvianolic acid B on Schwann cells apoptosis induced by high glucose." in: Neurochemical research, Vol. 37, Issue 5, pp. 996-1010, (2012) (PubMed).

Sun, Xue, Li, Wang, Qu, Zhang, Zhao, Wang, Zou, Mu, Lu: "Inhibitory effects of salvianolic acid B on apoptosis of Schwann cells and its mechanism induced by intermittent high glucose." in: Life sciences, Vol. 90, Issue 3-4, pp. 99-108, (2012) (PubMed).

Target Details for Histone 3

Target: Histone 3 (H3) (Histone H3 (H3))

Alternative Name: Histone H3

Background: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.  

Molecular Weight: 17 kDa

NCBI Accession: NP_003520, NM_003529

UniProt: P68431