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CD43 antibody

SPN Reactivity: Human FACS Host: Mouse Monoclonal DF-T1 unconjugated
Catalog No. ABIN135773
  • Target See all CD43 (SPN) Antibodies
    CD43 (SPN) (Sialophorin (SPN))
    Reactivity
    • 129
    • 16
    • 13
    • 1
    Human
    Host
    • 79
    • 68
    • 7
    Mouse
    Clonality
    • 86
    • 64
    • 4
    Monoclonal
    Conjugate
    • 71
    • 14
    • 14
    • 14
    • 7
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD43 antibody is un-conjugated
    Application
    • 87
    • 83
    • 51
    • 42
    • 42
    • 20
    • 17
    • 14
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificity
    Human CD43, Mr 95-135 kDa
    Characteristics
    Mouse Anti-Human CD43-UNLB
    Purification
    Purified
    Immunogen
    KG-1 cells
    Clone
    DF-T1
    Isotype
    IgG1
    Top Product
    Discover our top product SPN Primary Antibody
  • Application Notes
    • Applications: FC - Quality tested , IHC-FS - Reported in literature , IHC-PS - Reported in literature , ICC - Reported in literature , IP - Reported in literature , WB - Reported in literature , Adhesion - Reported in literature
    • Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC, BIOT, PE, APC, and SPRD conjugates 10 L/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    Sample Volume
    1 mL
    Restrictions
    For Research Use only
  • Concentration
    0.1 mg/mL
    Buffer
    0.1 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added
    Preservative
    Without preservative
    Handling Advice
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    Storage
    4 °C
    Storage Comment
    Store at 2-8°C
  • Target
    CD43 (SPN) (Sialophorin (SPN))
    Alternative Name
    CD43 (SPN Products)
    Background
    CD43, a member of the sialomucin family of cell surface receptors, is a 95-135 kDa type I transmembrane glycoprotein whose variability in molecular weight is dependent upon the nature of the extracellular O-glycans. It is the major sialoglycoprotein on thymocytes, T cells and neutrophils. It is also present on activated B cells, plasma cells, NK cells, granulocytes, monocytes, macrophages, platelets and bone marrow hematopoietic stem cells. CD43, which binds to ICAM-1 (CD54), appears to function as an anti-adhesion molecule, inhibiting T cell interactions, including T cell killing, and by increasing the threshold for T cell activation.
    Pathways
    Regulation of Leukocyte Mediated Immunity
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