c-MET antibody
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- Target See all c-MET (MET) Antibodies
- c-MET (MET) (Met Proto-Oncogene (MET))
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Reactivity
- Human
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Host
- Rat
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Clonality
- Monoclonal
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Conjugate
- This c-MET antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Cell-ELISA (cELISA)
- Specificity
- Anti-human c-Met
- Characteristics
- Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells
- Purification
- Protein G
- Immunogen
- genetic immunisation with cDNA encoding human c-Met
- Clone
- BCI-3E7
- Isotype
- IgG2b kappa
- Top Product
- Discover our top product MET Primary Antibody
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anti-Met Proto-Oncogene (MET) (AA 25-150) antibody
MET Reactivity: Human, Mouse WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Met Proto-Oncogene (MET) (AA 743-932) antibodyMET Reactivity: Human WB, ELISA, IHC, FACS, ICC Host: Mouse Monoclonal 5E9C4 unconjugated
anti-Met Proto-Oncogene (MET) (AA 1092-1379) antibodyMET Reactivity: Human WB, IHC, ICC, IP Host: Rabbit Polyclonal unconjugated
anti-Met Proto-Oncogene (MET) antibodyMET Reactivity: Human WB, ELISA, IHC, IF, FACS Host: Rabbit Monoclonal 2D12 unconjugated Recombinant Antibody
anti-Met Proto-Oncogene (MET) (AA 743-932) antibodyMET Reactivity: Human ELISA, FACS, ICC Host: Mouse Monoclonal 5E9B7 unconjugated
anti-Met Proto-Oncogene (MET) (C-Term) antibodyMET Reactivity: Human WB, IF, ICC, IP Host: Rabbit Polyclonal unconjugated
anti-Met Proto-Oncogene (MET) (Internal Region) antibodyMET Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Met Proto-Oncogene (MET) (Tyr1003) antibodyMET Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Met Proto-Oncogene (MET) (AA 83-209) antibodyMET Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Met Proto-Oncogene (MET) (pTyr1234) antibodyMET Reactivity: Human, Mouse, Rat WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
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- Application Notes
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Flow cytometry: 1.2 µg/10^6 cells
CELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration. - Restrictions
- For Research Use only
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- Buffer
- PBS, pH 7.2
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C
- Storage Comment
- short term: 2 °C - 8 °C, long term: -20 °C
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- Target
- c-MET (MET) (Met Proto-Oncogene (MET))
- Alternative Name
- c-Met (MET Products)
- Background
- C-MET is a receptor tyrosine kinase that is activated upon Hepatocyte Growth Factor (HGF) binding. c-MET is produced as a single-chain precursor and plays en essential role in embryonic development and wound healing. It belongs to the class of Single-pass type I membrane proteins and it is normally expressed by cells of epithelial origin while the expression of HGF is restricted to cells of mesenchymal origin in an almost perfect paracrine paradigm. Overexpression of c-MET can be found in several kinds of tumor progression.
- UniProt
- P08581
- Pathways
- RTK Signaling, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor
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