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c-MET antibody (C-Term)

MET Reactivity: Human WB, IF, ICC, IP Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2854819
  • Target See all c-MET (MET) Antibodies
    c-MET (MET) (Met Proto-Oncogene (MET))
    Binding Specificity
    • 49
    • 35
    • 28
    • 21
    • 16
    • 11
    • 11
    • 8
    • 7
    • 7
    • 7
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 250
    • 144
    • 98
    • 8
    • 6
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 221
    • 39
    • 3
    • 2
    Rabbit
    Clonality
    • 209
    • 56
    Polyclonal
    Conjugate
    • 131
    • 20
    • 13
    • 12
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 8
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    This c-MET antibody is un-conjugated
    Application
    • 181
    • 105
    • 51
    • 43
    • 30
    • 27
    • 26
    • 24
    • 14
    • 8
    • 7
    • 7
    • 4
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP)
    Cross-Reactivity
    Chimpanzee
    Cross-Reactivity (Details)
    Chimpanzee (100 %)
    Characteristics
    Rabbit Polyclonal antibody to MET (met proto-oncogene (hepatocyte growth factor receptor))
    c-Met antibody [C3], C-term
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human c-Met. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product MET Primary Antibody
  • Application Notes
    Suggested dilution Reference ICC/IF 1:100-1:1000* Immunoprecipitation 1:100-1:500* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Immunoprecipitation1:100-1:500* Western blot1:500-1:3000*
    Comment

    Positive Control: HeLaS3

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    c-MET (MET) (Met Proto-Oncogene (MET))
    Alternative Name
    C-Met (MET Products)
    Synonyms
    AUTS9 antibody, HGFR antibody, RCCP2 antibody, c-Met antibody, AI838057 antibody, HGF antibody, Par4 antibody, Hgfr antibody, c-met antibody, MET antibody, C-MET antibody, met antibody, met-A antibody, MET proto-oncogene, receptor tyrosine kinase antibody, met proto-oncogene antibody, MET proto-oncogene, receptor tyrosine kinase L homeolog antibody, MET antibody, Met antibody, met.L antibody
    Background
    The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene.

    Cellular Localization: Membrane, Single-pass type I membrane protein
    Molecular Weight
    156 kDa
    Gene ID
    4233
    Pathways
    RTK Signaling, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor
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