IL-6 Receptor antibody

Catalog No. ABIN1383675

Cited in 2+ publications. The Mouse Monoclonal anti-IL-6 Receptor antibody (Clone B-F19) (ABIN1383675) specifically detects IL-6 Receptor in IHC, ELISA and FACS. The antibody is reactive with Human samples.

Quick Overview for IL-6 Receptor antibody (ABIN1383675)

Target: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL-6 Receptor antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Clone: B-F19

Product Details anti-IL-6 Receptor Antibody

Specificity: Recognises the Interleukin-6 Ra subunit, IL-6 Ra, IL-6 R, a 80 kDa protein

Purification: Ion exchange chromatography

Sterility: 0.22 μm filtered

Immunogen: gp80 transfected CHO cell line,Myeloma X63/AG.8653 x Balb/c spleen cells

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free

Preservative: Without preservative

Storage: 4 °C

Storage Comment: Stable at +2-8°C for 12 months. For longer storage freeze aliquots.

References for anti-IL-6 Receptor antibody (ABIN1383675)

Larregina, Morelli, Kolkowski, Sanjuan, Barboza, Fainboim: "Pattern of cytokine receptors expressed by human dendritic cells migrated from dermal explants." in: Immunology, Vol. 91, Issue 2, pp. 303-13, (1997) (PubMed).

Mouthon, Freund, Titeux, Katz, Guichard, Breton-Gorius, Vainchenker: "Growth and differentiation of the human megakaryoblastic cell line (ELF-153): a model for early stages of megakaryocytopoiesis." in: Blood, Vol. 84, Issue 4, pp. 1085-97, (1994) (PubMed).

Target Details for IL-6 Receptor

Target: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Alternative Name: CD126

Background: IL-6R / gp80

Molecular Weight: 80 kDa

Pathways: JAK-STAT Signaling, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints