CD44 antibody

Catalog No. ABIN1383707

The Mouse Monoclonal anti-CD44 antibody has been validated for FACS, ELISA, IP and Func. It is suitable to detect CD44 in samples from Human. There are 3+ publications available.

Quick Overview for CD44 antibody (ABIN1383707)

Target: CD44

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD44 antibody is un-conjugated

Application: Flow Cytometry (FACS), ELISA, Immunoprecipitation (IP), Functional Studies (Func)

Clone: B-F24

Product Details anti-CD44 Antibody

Specificity: Recognises the Hyaluronate Cell Adhesion Molecule (H-CAM), a 85-250 kDa protein

Purification: Ion exchange chromatography

Sterility: 0.22 μm filtered

Immunogen: U937 cell line,Myeloma X63/AG.8653 x Balb/c spleen cells

Isotype: IgG1 kappa

Biological Activity Comment: Triggers T-lymphocyte aggregation. Enhances Hyaluronan binding to CD44

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free

Preservative: Without preservative

Storage: 4 °C

Storage Comment: Stable at +2-8°C for 12 months. For longer storage freeze aliquots.

References for anti-CD44 antibody (ABIN1383707)

Lefevre, Krzysiek, Loret, Galanaud, Richard: "Cutting edge: HIV-1 Tat protein differentially modulates the B cell response of naive, memory, and germinal center B cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 163, Issue 3, pp. 1119-22, (1999) (PubMed).

Vermot-Desroches, Marchand, Roy, Wijdenes: "Heterogeneity of antigen expression among human umbilical cord vascular endothelial cells: identification of cell subsets by co-expression of haemopoietic antigens." in: Immunology letters, Vol. 48, Issue 1, pp. 1-9, (1996) (PubMed).

Vermot-Desroches, Wijdenes, Valmu, Roy, Pigott, Nortamo, Gahmberg: "A CD44 monoclonal antibody differentially regulates CD11a/CD18 binding to intercellular adhesion molecules CD54, CD102 and CD50." in: European journal of immunology, Vol. 25, Issue 9, pp. 2460-4, (1995) (PubMed).

Target Details for CD44

Target: CD44

Alternative Name: CD44

Background: Pgp-1, H-CAM

Molecular Weight: 85-250 kDa

Pathways: Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling