ICAM1 antibody

Catalog No. ABIN1383713

The Mouse Monoclonal anti-ICAM1 antibody has been validated for FACS, ELISA, IP and Func. It is suitable to detect ICAM1 in samples from Human. There are 3+ publications available.

Quick Overview for ICAM1 antibody (ABIN1383713)

Target: ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ICAM1 antibody is un-conjugated

Application: Flow Cytometry (FACS), ELISA, Immunoprecipitation (IP), Functional Studies (Func)

Clone: B-H17

Product Details anti-ICAM1 Antibody

Specificity: Recognises the Intercellular Adhesion Molecule-1 (ICAM-1), a 75-115 kDa protein

Purification: Ion exchange chromatography

Sterility: 0.22 μm filtered

Immunogen: Activated human umbilical vein endothelial (HUVEC),Myeloma X63/AG.8653 x Balb/c spleen cells

Isotype: IgG1 kappa

Biological Activity Comment: Inhibits PHA stimulated T-cell proliferation

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free

Preservative: Without preservative

Storage: 4 °C

Storage Comment: Stable at +2-8°C for 12 months. For longer storage freeze aliquots.

References for anti-ICAM1 antibody (ABIN1383713)

Cie?lik, Hrycek: "Pentraxin 3 as a biomarker of local inflammatory response to vascular injury in systemic lupus erythematosus." in: Autoimmunity, pp. 1-9, (2014) (PubMed).

Ticchioni, Raimondi, Lamy, Wijdenes, Lindberg, Brown, Bernard: "Integrin-associated protein (CD47/IAP) contributes to T cell arrest on inflammatory vascular endothelium under flow." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 15, Issue 2, pp. 341-50, (2001) (PubMed).

Vermot-Desroches, Marchand, Roy, Wijdenes: "Heterogeneity of antigen expression among human umbilical cord vascular endothelial cells: identification of cell subsets by co-expression of haemopoietic antigens." in: Immunology letters, Vol. 48, Issue 1, pp. 1-9, (1996) (PubMed).

Target Details for ICAM1

Target: ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

Alternative Name: CD54

Background: ICAM-1

Molecular Weight: 75-115 kDa

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling