TNFRSF10A antibody

Catalog No. ABIN1383733

This Mouse Monoclonal antibody specifically detects TNFRSF10A in WB and IP. It exhibits reactivity toward Human. It has been mentioned in 4+ publications

Quick Overview for TNFRSF10A antibody (ABIN1383733)

Target: TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TNFRSF10A antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Clone: B-N28

Product Details anti-TNFRSF10A Antibody

Specificity: Recognises a 43-46 kDa protein

Purification: Ion exchange chromatography

Sterility: 0.22 μm filtered

Immunogen: Recombinant human TRAIL R1/Fc chimera,Myeloma X63/AG.8653 x Balb/c spleen cells

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free

Preservative: Without preservative

Storage: 4 °C

Storage Comment: Stable at +2-8°C for 12 months

References for anti-TNFRSF10A antibody (ABIN1383733)

Lin, Chen, Yue, Zou, Benbrook, Liu, Le, Berlin, Khuri, Sun: "CAAT/enhancer binding protein homologous protein-dependent death receptor 5 induction is a major component of SHetA2-induced apoptosis in lung cancer cells." in: Cancer research, Vol. 68, Issue 13, pp. 5335-44, (2008) (PubMed).

Raja, Chen, Yue, Acker, Lefkove, Arbiser, Khuri, Sun: "The natural product honokiol preferentially inhibits cellular FLICE-inhibitory protein and augments death receptor-induced apoptosis." in: Molecular cancer therapeutics, Vol. 7, Issue 7, pp. 2212-23, (2008) (PubMed).

Chen, Liu, Yue, Schönthal, Khuri, Sun et al.: "CCAAT/enhancer binding protein homologous protein-dependent death receptor 5 induction and ubiquitin/proteasome-mediated cellular FLICE-inhibitory protein down-regulation contribute to enhancement of ..." in: Molecular pharmacology, Vol. 72, Issue 5, pp. 1269-79, (2007) (PubMed).

Vermot-Desroches, Sergent, Bonnin, Wijdenes: "Characterization of monoclonal antibodies directed against trail or trail receptors." in: Cellular immunology, Vol. 236, Issue 1-2, pp. 86-91, (2005) (PubMed).

Target Details for TNFRSF10A

Target: TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))

Alternative Name: TRAIL R1

Background: DR4, TRAIL R1

Molecular Weight: 43-46 kDa

Pathways: Apoptosis, Positive Regulation of Endopeptidase Activity