MME antibody

Catalog No. ABIN1383814

This Mouse Monoclonal antibody specifically detects MME in FACS, IHC and Func. It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for MME antibody (ABIN1383814)

Target: MME (Membrane Metallo-Endopeptidase (MME))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MME antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Functional Studies (Func)

Clone: B-E3

Product Details anti-MME Antibody

Specificity: Recognises the Common Acute Lymphoblastic Leukemia Antigen (CALLA), a 100 kDa protein

Purification: Ion exchange chromatography

Sterility: 0.22 μm filtered

Immunogen: Daudi and Raji cell lines,Myeloma X63/AG.8653 x Balb/c spleen cells

Isotype: IgG2a, kappa

Biological Activity Comment: Cytotoxic In association with rabbit complement on CD10+ cells

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free

Preservative: Without preservative

Storage: 4 °C

Storage Comment: Stable at +2-8°C for 12 months. For longer storage freeze aliquots.

References for anti-MME antibody (ABIN1383814)

Geijtenbeek, van Kooyk, van Vliet, Renes, Raymakers, Figdor: "High frequency of adhesion defects in B-lineage acute lymphoblastic leukemia." in: Blood, Vol. 94, Issue 2, pp. 754-64, (1999) (PubMed).

van den Berg, van Die, de Lavalette, Döpp, Smit, van der Meide, Tilders, Crocker, Dijkstra: "Regulation of sialoadhesin expression on rat macrophages. Induction by glucocorticoids and enhancement by IFN-beta, IFN-gamma, IL-4, and lipopolysaccharide." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 157, Issue 7, pp. 3130-8, (1996) (PubMed).

Target Details for MME

Target: MME (Membrane Metallo-Endopeptidase (MME))

Alternative Name: CD10

Background: CALLA

Molecular Weight: 100 kDa

Pathways: RTK Signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration