TNFRSF10A antibody

Catalog No. ABIN1383909

Cited in 1 publication. The Mouse Monoclonal anti-TNFRSF10A antibody (Clone B-N36) (ABIN1383909) specifically detects TNFRSF10A in FACS, ELISA and Func. The antibody is reactive with Human samples.

Quick Overview for TNFRSF10A antibody (ABIN1383909)

Target: TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TNFRSF10A antibody is un-conjugated

Application: Flow Cytometry (FACS), ELISA, Functional Studies (Func)

Clone: B-N36

Product Details anti-TNFRSF10A Antibody

Specificity: Recognises a 43-46 kDa protein

Purification: Ion exchange chromatography

Sterility: 0.22 μm filtered

Immunogen: Recombinant human TRAIL R1/Fc chimera,Myeloma X63/AG.8653 x Balb/c spleen cells

Isotype: IgG1 kappa

Biological Activity Comment: Neutralizes TRAIL induced apoptosis on HEL cell line

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free

Preservative: Without preservative

Storage: 4 °C

Storage Comment: Stable at +2-8°C for 12 months. For longer storage freeze aliquots.

References for anti-TNFRSF10A antibody (ABIN1383909)

Vermot-Desroches, Sergent, Bonnin, Wijdenes: "Characterization of monoclonal antibodies directed against trail or trail receptors." in: Cellular immunology, Vol. 236, Issue 1-2, pp. 86-91, (2005) (PubMed).

Target Details for TNFRSF10A

Target: TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))

Alternative Name: TRAIL R1

Background: DR4, TRAIL R1

Molecular Weight: 43-46 kDa

Pathways: Apoptosis, Positive Regulation of Endopeptidase Activity