PVRL2 antibody

Catalog No. ABIN1384013

There are 2+ publications for this product available. The Mouse Monoclonal anti-PVRL2 antibody is suitable to detect PVRL2 in samples from Human. It has been validated for FACS, ELISA and IP.

Quick Overview for PVRL2 antibody (ABIN1384013)

Target: PVRL2 (Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PVRL2 antibody is un-conjugated

Application: Flow Cytometry (FACS), ELISA, Immunoprecipitation (IP)

Clone: B-C12

Product Details anti-PVRL2 Antibody

Specificity: Recognises Nectin-2, the polio retrovirus receptor-2 (PRR2)

Purification: Ion exchange chromatography

Sterility: 0.22 μm filtered

Immunogen: KG-1 cell line,Myeloma X63/AG.8653 x Balb/c spleen cells

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free

Preservative: Without preservative

Storage: 4 °C

Storage Comment: Stable at +2-8°C for 12 months. For longer storage freeze aliquots.

References for anti-PVRL2 antibody (ABIN1384013)

Lopez, Cocchi, Menotti, Avitabile, Dubreuil, Campadelli-Fiume: "Nectin2alpha (PRR2alpha or HveB) and nectin2delta are low-efficiency mediators for entry of herpes simplex virus mutants carrying the Leu25Pro substitution in glycoprotein D." in: Journal of virology, Vol. 74, Issue 3, pp. 1267-74, (2000) (PubMed).

Lopez, Aoubala, Jordier, Isnardon, Gomez, Dubreuil: "The human poliovirus receptor related 2 protein is a new hematopoietic/endothelial homophilic adhesion molecule." in: Blood, Vol. 92, Issue 12, pp. 4602-11, (1999) (PubMed).

Target Details for PVRL2

Target: PVRL2 (Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2))

Alternative Name: CD112

Background: HVEB, PRR2

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization