EV71 VP1 antibody

Catalog No. ABIN1385106

Product Details anti-EV71 VP1 Antibody

Target: EV71 VP1 (Enterovirus 71 VP1 (EV71 VP1))

Reactivity: Enterovirus (EV71)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EV71 VP1 antibody is un-conjugated

Application: Immunofluorescence (Cultured Cells) (IF (cc))

Cross-Reactivity: Human, Virus

Cross-Reactivity (Details): Enterovirus EV71

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from EV71 polyprotein VP1

Isotype: IgG

Application Details

Application Notes: ELISA(1:5000-10000)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-EV71 VP1 antibody (ABIN1385106)

Wang, Zhou, Zhang, Jin, Cardona, Xing: "Intrinsic apoptosis and proinflammatory cytokines regulated in human astrocytes infected with enterovirus 71." in: The Journal of general virology, Vol. 96, Issue 10, pp. 3010-22, (2016) (PubMed).

Target Details for EV71 VP1

Target: EV71 VP1 (Enterovirus 71 VP1 (EV71 VP1))

Abstract: EV71 VP1 Products

Target Type: Viral Protein

Background:

Synonyms: EV71, Enterovirus 71, VP1 [Human enterovirus 71],polyprotein VP1, Human enterovirus 71.

Background: Enteroviruses, such as enterovirus 71, are classified to be in the picornavirus family, pico [small] + RNA [ribonucleic acid] + virus. Picornaviruses are among the smallest and simplest ribonucleic acid containing viruses known (1). The RNA for many enteroviruses have now been cloned and complete genomic sequences have been obtained. The RNA from all sequenced enteroviruses are similar in length, about 7400 nucleotides, and have identical organization (1). The human alimentary tract is the predominant site of enterovirus replication and these viruses were first isolated from enteric specimens. These viruses are the cause of paralytic poliomyelitis, aseptic meningitis-encephalitis, myocarditis, pleurodynia, hand-foot-and-mouth disease, conjunctivitis, and numerous other syndromes associated with extra-intestinal target organs. There are 67 numbered types of enteroviruses in the enterovirus family (1): three polioviruses, twenty-three coxsackieviruses A, six coxsackieviruses B, thirty-one echoviruses, and four other enteroviruses.