MARCH11 antibody

Catalog No. ABIN1385392

This Rabbit Polyclonal antibody specifically detects MARCH11 in IF (p) and IHC (p). It exhibits reactivity toward Human.

Quick Overview for MARCH11 antibody (ABIN1385392)

Target: MARCH11 (Membrane-Associated Ring Finger (C3HC4) 11 (MARCH11))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MARCH11 antibody is un-conjugated

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-MARCH11 Antibody

Purpose: MARCH11 Polyclonal Antibody

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Sheep,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MARCH11

Isotype: IgG

Application Details

Application Notes: IHC-P(1:200-400), IF(IHC-P)(1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for MARCH11

Target: MARCH11 (Membrane-Associated Ring Finger (C3HC4) 11 (MARCH11))

Alternative Name: MARCH11

Background:

Synonyms: E3 ubiquitin-protein ligase MARCH11, MARCH-XI, March11, MARHB_HUMAN, Membrane associated ring finger C3HC4 11, Membrane-associated RING finger protein 11, Membrane-associated RING-CH protein XI.

Background: E3 ubiquitin-protein ligase that mediates polyubiquitination of CD4. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. May play a role in ubuquitin-dependent protein sorting in developmenting spermatids.

Gene ID: 441061