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PGBD3 antibody (AA 410-460)

PGBD3 Reactivity: Human WB, IHC (p), IF (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1385394
  • Target See all PGBD3 Antibodies
    PGBD3 (PiggyBac Transposable Element Derived 3 (PGBD3))
    Binding Specificity
    • 13
    • 7
    • 1
    • 1
    AA 410-460
    Reactivity
    • 17
    • 1
    • 1
    Human
    Host
    • 17
    Rabbit
    Clonality
    • 17
    Polyclonal
    Conjugate
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    This PGBD3 antibody is un-conjugated
    Application
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human PGBD3
    Isotype
    IgG
    Top Product
    Discover our top product PGBD3 Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    PGBD3 (PiggyBac Transposable Element Derived 3 (PGBD3))
    Alternative Name
    PGBD3 (PGBD3 Products)
    Synonyms
    PGBD3 antibody, piggyBac transposable element derived 3 antibody, ERCC excision repair 6, chromatin remodeling factor antibody, PGBD3 antibody, ERCC6 antibody
    Background

    Synonyms: PGBD 3, PiggyBac transposable element derived 3, PiggyBac transposable element derived protein 3, PGBD3_HUMAN.

    Background: PiggyBac transposable element derived 3, also known as PGBD3, encodes a 593 amino acid transposase and is a member of the piggyBac transposable element derived (PGBD) gene family, which includes several genes that are derived from piggyBac transposons. Initially characterized in the cabbacge looper moth, Trichoplusia ni, the PGBD family is conserved in a wide variety of species, including protozoa and primates. More specifically, while PGBD3 and PGBD4 are primate-specific genes, the other three members of the PGBD family (namely PGBD1, PGBD2 and PGBD5) are conserved among a variety of vertebrates. PGBD3 appears to be novel, with no clear relationship to other transposases or other known protein families. However, the PGBD3 gene overlaps with the CSB gene on chromosome 10 and, with the CSB gene, plays a role in Cockayne syndrome, a rare disorder characterized by premature aging, microcephaly, photosensitivity and severe neurologic degeneration.

    Gene ID
    267004
    UniProt
    Q8N328
    Pathways
    Chromatin Binding
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