PROZ antibody

Catalog No. ABIN1385423

The Rabbit Polyclonal anti-PROZ antibody has been validated for WB, IF (p) and IHC (p). It is suitable to detect PROZ in samples from Human.

Quick Overview for PROZ antibody (ABIN1385423)

Target: PROZ (Protein Z, Vitamin K-Dependent Plasma Glycoprotein (PROZ))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PROZ antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PROZ Antibody

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Protein Z

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for PROZ

Target: PROZ (Protein Z, Vitamin K-Dependent Plasma Glycoprotein (PROZ))

Alternative Name: Protein Z

Background:

Synonyms: Protein Z, vitamin K dependent plasma glycoprotein, PROZ, PROZ_HUMAN, PZ antibody Vitamin K-dependent protein Z.

Background: This gene encodes a liver vitamin K-dependent glycoprotein that is synthesized in the liver and secreted into the plasma. The encoded protein plays a role in regulating blood coagulation by complexing with protein Z-dependent protease inhibitor to directly inhibit activated factor X at the phospholipid surface. Deficiencies in this protein are associated with an increased risk of ischemic arterial diseases and fetal loss. Mutations in this gene are the cause of protein Z deficiency. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012].

Gene ID: 8858