PROZ antibody

Catalog No. ABIN7075303

Product Details anti-PROZ Antibody

Target: PROZ (Protein Z, Vitamin K-Dependent Plasma Glycoprotein (PROZ))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PROZ antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse Protein Z

Application Details

Application Notes: WB (M,R) 1:500- 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for PROZ

Target: PROZ (Protein Z, Vitamin K-Dependent Plasma Glycoprotein (PROZ))

Alternative Name: Protein Z (PROZ Products)

Synonyms: PZ antibody, 1300015B06Rik antibody, betaH1 antibody, protein Z, vitamin K dependent plasma glycoprotein antibody, protein Z, vitamin K-dependent plasma glycoprotein antibody, protein Z, vitamin K-dependent plasma glycoprotein b antibody, hemoglobin Z, beta-like embryonic chain antibody, PROZ antibody, Proz antibody, prozb antibody, Hbb-bh1 antibody

Background: This gene encodes a liver vitamin K-dependent glycoprotein that is synthesized in the liver and secreted into the plasma. The encoded protein plays a role in regulating blood coagulation by complexing with protein Z-dependent protease inhibitor to directly inhibit activated factor X at the phospholipid surface. Deficiencies in this protein are associated with an increased risk of ischemic arterial diseases and fetal loss. Mutations in this gene are the cause of protein Z deficiency. Alternate splicing results in multiple transcript variants.

Molecular Weight: 50 kDa

Gene ID: 66901

UniProt: Q9CQW3