PROZ antibody
Quick Overview for PROZ antibody (ABIN7075303)
Target
See all PROZ AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Cross-Reactivity
- Rat
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Purification
- Affinity purification
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Immunogen
- Recombinant protein corresponding to Mouse Protein Z
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Application Notes
- WB (M,R) 1:500- 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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- PROZ (Protein Z, Vitamin K-Dependent Plasma Glycoprotein (PROZ))
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Alternative Name
- Protein Z
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Background
- This gene encodes a liver vitamin K-dependent glycoprotein that is synthesized in the liver and secreted into the plasma. The encoded protein plays a role in regulating blood coagulation by complexing with protein Z-dependent protease inhibitor to directly inhibit activated factor X at the phospholipid surface. Deficiencies in this protein are associated with an increased risk of ischemic arterial diseases and fetal loss. Mutations in this gene are the cause of protein Z deficiency. Alternate splicing results in multiple transcript variants.
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Molecular Weight
- 50 kDa
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Gene ID
- 66901
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UniProt
- Q9CQW3
Target
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