AKD1 antibody

Catalog No. ABIN1385425

Product Details anti-AKD1 Antibody

Target: AKD1 (ADK1) (Adenylate Kinase Domain Containing 1 (ADK1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AKD1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human AKD1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for AKD1

Target: AKD1 (ADK1) (Adenylate Kinase Domain Containing 1 (ADK1))

Alternative Name: AKD1 (ADK1 Products)

Background:

Synonyms: adenylate kinase domain containing 1, adenylate kinase domain containing 2, Adenylate kinase domain-containing protein 1, Adenylate kinase domain-containing protein 2, AKD1, AKD1_HUMAN, AKD2 , C6orf224, chromosome 6 open reading frame 199, chromosome 6 open reading frame 224 Gm234, Gm7127, RP1-70A9.

Background: AKD1 is a 1,911 amino acid coiled-coil protein belonging to the adenylate kinase family. AKD1 exists as six alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 6q21. Chromosome 6 makes up nearly 6 % of the human genome and contains 170 million base pairs, which encode 1,200 genes. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. A bipolar disorder susceptibility locus is also linked to the q arm of chromosome 6. The PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins are located on chromosome 6. Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6.