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FBXL5 antibody (AA 31-130)

FBXL5 Reactivity: Human WB, FACS, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1385651
  • Target See all FBXL5 Antibodies
    FBXL5 (F-Box and Leucine-Rich Repeat Protein 5 (FBXL5))
    Binding Specificity
    • 15
    • 10
    • 9
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 31-130
    Reactivity
    • 46
    • 16
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 43
    • 3
    Rabbit
    Clonality
    • 45
    Polyclonal
    Conjugate
    • 21
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FBXL5 antibody is un-conjugated
    Application
    • 42
    • 27
    • 22
    • 21
    • 5
    Western Blotting (WB), Flow Cytometry (FACS), ELISA
    Cross-Reactivity
    Human
    Predicted Reactivity
    Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human FBXL5
    Isotype
    IgG
    Top Product
    Discover our top product FBXL5 Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    FBXL5 (F-Box and Leucine-Rich Repeat Protein 5 (FBXL5))
    Alternative Name
    FBXL5 (FBXL5 Products)
    Synonyms
    fbxl5 antibody, MGC53238 antibody, FBXL5 antibody, FBL4 antibody, FBL5 antibody, FLR1 antibody, Fbl4 antibody, Fir4 antibody, wu:fb52d06 antibody, F-box and leucine rich repeat protein 5 antibody, F-box and leucine-rich repeat protein 5 S homeolog antibody, F-box and leucine-rich repeat protein 5 L homeolog antibody, F-box and leucine-rich repeat protein 5 antibody, FBXL5 antibody, fbxl5.S antibody, fbxl5.L antibody, fbxl5 antibody, Fbxl5 antibody
    Background

    Synonyms: F box and leucine rich repeat protein 5, F box/LRR repeat protein 5, F-box and leucine-rich repeat protein 5, F-box protein FBL4/FBL5, F-box/LRR-repeat protein 5, FBL4, FBL5, FBXL5, FBXL5_HUMAN, FLR1, p45SKP2 like protein, p45SKP2-like protein.

    Background: Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in iron homeostasis by promoting the ubiquitination and subsequent degradation of IREB2/IRP2. Upon high iron and oxygen level, it specifically recognizes and binds IREB2/IRP2, promoting its ubiquitination and degradation by the proteasome. Promotes ubiquitination and subsequent degradation of DCTN1/p150-glued.

    Gene ID
    26234
    Pathways
    Transition Metal Ion Homeostasis
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