DRAXIN antibody

Catalog No. ABIN1385811

The Rabbit Polyclonal anti-DRAXIN antibody (ABIN1385811) specifically detects DRAXIN in WB, IF (p) and IHC (p). The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for DRAXIN antibody (ABIN1385811)

Target: DRAXIN (Dorsal Inhibitory Axon Guidance Protein (DRAXIN))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DRAXIN antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-DRAXIN Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C1orf187

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for DRAXIN

Target: DRAXIN (Dorsal Inhibitory Axon Guidance Protein (DRAXIN))

Alternative Name: C1orf187

Background:

Synonyms: AGPA3119, C1orf187, Chromosome 1 open reading frame 187, Dorsal repulsive axon guidance protein, DRAXI_HUMAN, Draxin, Neucrin, UNQ3119.

Background: Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.

Gene ID: 374946