CTDNEP1A antibody (AA 121-200)

Catalog No. ABIN1385846

The Rabbit Polyclonal anti-CTDNEP1A antibody has been validated for ELISA, WB, IHC (p), ICC, IF (cc), IF (p) and IHC (fro). It is suitable to detect CTDNEP1A in samples from Mouse.

Quick Overview for CTDNEP1A antibody (AA 121-200) (ABIN1385846)

Target: CTDNEP1A (CTD Nuclear Envelope Phosphatase 1a (CTDNEP1A))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CTDNEP1A antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-CTDNEP1A Antibody

Binding Specificity: AA 121-200

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DULLARD

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for CTDNEP1A

Target: CTDNEP1A (CTD Nuclear Envelope Phosphatase 1a (CTDNEP1A))

Alternative Name: DULLARD

Background:

Synonyms: Dullard homolog, HSA 011916, NET 56 antibodySerine threonine protein phosphatase dullard, CNEP1_HUMAN.

Background: In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. Dullard, also known as NET56, is a 244 amino acid single-pass membrane protein that localizes to both the nucleus and the endoplasmic reticulum and contains one FCP1 homology domain. Functioning as a serine/threonine phosphatase, Dullard catalyses the dephosphorylation of target proteins and is thought to be required for proper nuclear membrane morphology. Human Dullard shares 92 % sequence identity with its zebrafish counterpart, suggesting a conserved role between species.