TPP1 antibody (AA 401-500)

Catalog No. ABIN1385927

The Rabbit Polyclonal anti-TPP1 antibody has been validated for WB, ELISA, IF (cc), IF (p), IHC (p) and IHC (fro). It is suitable to detect TPP1 in samples from Human and Mouse.

Quick Overview for TPP1 antibody (AA 401-500) (ABIN1385927)

Target: TPP1 (Tripeptidyl Peptidase I (TPP1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TPP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-TPP1 Antibody

Binding Specificity: AA 401-500

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TPP1/CLN2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for TPP1

Target: TPP1 (Tripeptidyl Peptidase I (TPP1))

Alternative Name: TPP1

Background:

Synonyms: Cell growth inhibiting gene 1 protein, Cell growth-inhibiting gene 1 protein, Ceroid lipofuscinosis neuronal 2, Ceroid lipofuscinosis neuronal 2 late infantile Jansky Bielschowsky disease, Ceroid lipofuscinosis neuronal 2 late infantile antibody CLN 2, CLN2, CLN-2, GIG 1, GIG1, Growth inhibiting protein 1, LPIC, Lysosomal pepstatin insensitive protease, Lysosomal pepstatin-insensitive protease, TPP 1, TPP I, TPP-1, TPP-I, Tpp1, TPP1_HUMAN, TPPI, Tripeptidyl aminopeptidase, Tripeptidyl peptidase I, Tripeptidyl-peptidase 1, Tripeptidyl-peptidase I.

Background: Lysosomal serine protease with tripeptidyl-peptidase I activity. May act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases. Requires substrates with an unsubstituted N-terminus.

Gene ID: 1200

Pathways: Cell Division Cycle, ER-Nucleus Signaling