HARBI1 antibody

Catalog No. ABIN1385991

Product Details anti-HARBI1 Antibody

Target: HARBI1 (Harbinger Transposase Derived 1 (HARBI1))

Reactivity: Mouse, Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HARBI1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C11ORF77/HARBI1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for HARBI1

Target: HARBI1 (Harbinger Transposase Derived 1 (HARBI1))

Alternative Name: C11ORF77 (HARBI1 Products)

Synonyms: C11orf77 antibody, C15H11orf77 antibody, D230010M03Rik antibody, flj32675 antibody, zgc:91866 antibody, harbinger transposase derived 1 antibody, HARBI1 antibody, Harbi1 antibody, harbi1 antibody

Background:

Synonyms: Chromosome 11 open reading frame 77, FLJ32675, HARB1_HUMAN, HARBI1, Harbinger transposase derived 1, Harbinger transposase-derived nuclease, Putative nuclease HARBI1.

Background: HARBI1 is a 349 amino acid nuclear and cytoplasmic protein belonging to the HARBI1 family. Members of the HARBI1 family of proteins are highly conserved in humans to various bony fish. Considered a transposase-derived protein, HARBI1 may possess nuclease activity and is expressed in brain, eye, nerve tissue, kidney and lung. HARBI1 utilizes divalent metal cations as cofactors, interacts with NAIF1 and promotes translocation to the nucleus. HARBI1 is encoded by a gene located on human chromosome 11, which houses over 1,400 genes and comprises nearly 4 % of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.