Glutamate Receptor 1 antibody (pSer849)

Catalog No. ABIN1386216

This anti-Glutamate Receptor 1 antibody is a Rabbit Polyclonal antibody detecting Glutamate Receptor 1 in WB, ELISA, IF (cc), IF (p), IHC (p) and IHC (fro). Suitable for Human, Rat and Mouse.

Quick Overview for Glutamate Receptor 1 antibody (pSer849) (ABIN1386216)

Target: Glutamate Receptor 1 (GLUR1)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glutamate Receptor 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Glutamate Receptor 1 Antibody

Binding Specificity: pSer849

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human GluR1 around the phosphorylation site of Ser849 [QQ(p-S)IN]

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Glutamate Receptor 1

Target: Glutamate Receptor 1 (GLUR1)

Alternative Name: GluR1

Background:

Synonyms: GluR1 phospho Ser849, GluR1 phospho S849, p- GluR1Ser849, p- GluR1S849, GLUR 1, GLUR A, AMPA 1, AMPA selective glutamate receptor 1, GLUH 1, GLUH1, GluR K1, GluR-1, GluR-A, GluR-K1, GLUR1, GLURA , GluRK1, Glutamate receptor 1, Glutamate receptor ionotropic AMPA 1, Gria 1, Gria1 , Gria1, HBGR1, MGC133252.

Background: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Gene ID: 2890

Pathways: PI3K-Akt Signaling