LIN7C antibody (AA 86-197)

Catalog No. ABIN1386222

Product Details anti-LIN7C Antibody

Target: LIN7C (Lin-7 Homolog C (LIN7C))

Binding Specificity: AA 86-197

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LIN7C antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Zebrafish

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LIN7C

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for LIN7C

Target: LIN7C (Lin-7 Homolog C (LIN7C))

Alternative Name: LIN7C (LIN7C Products)

Synonyms: LIN7C antibody, fb75b09 antibody, wu:fb75b09 antibody, zgc:101881 antibody, LIN-7-C antibody, LIN-7C antibody, MALS-3 antibody, MALS3 antibody, VELI3 antibody, 9130007B12Rik antibody, AI303698 antibody, AU019331 antibody, AW125731 antibody, D2Ertd520e antibody, Veli3 antibody, lin-7 homolog C, crumbs cell polarity complex component antibody, lin-7 homolog C L homeolog antibody, lin-7 homolog C (C. elegans) antibody, LIN7C antibody, lin7c.L antibody, lin7c antibody, Lin7c antibody

Background:

Synonyms: LIN 7 C, Lin 7 homolog C C. elegans, LIN 7 protein 3, LIN 7C, LIN7 protein 3, MALS 3, MALS3, Mammalian lin seven protein 3, Veli 3 protein, VELI3, Vertebrate lin 7 homolog 3, LIN7C_HUMAN.

Background: Velis are a family of small synaptic proteins that interact with other proteins at the post-synaptic density (PSD) of neuronal synapses. Velis contain the PDZ motif involved in recruiting cell adhesion molecules, receptors, and channels. Veli1 (also designated Lin-7A and MALS-1), Veli2 (also designated Lin-7B and MALS-2), and Veli3 (also designated Lin-7C and MALS-3) are mammalian homologs of C. elegans LIN-7. Veli proteins are ubiquitously expressed with high expression in brain, liver, and testis. Velis are localized at the synaptic junctions in neurons. Velis bind to CASK, a neurexin-binding protein highly concentrated in synapses, and Mint1, a binding partner with a vesicle trafficking protein.

Pathways: Synaptic Membrane