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MED7 antibody (AA 101-200)

MED7 Reactivity: Human WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p), ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1386223
  • Target See all MED7 Antibodies
    MED7 (Mediator Complex Subunit 7 (MED7))
    Binding Specificity
    • 14
    • 10
    • 7
    • 7
    • 6
    • 6
    • 4
    • 3
    • 2
    • 1
    AA 101-200
    Reactivity
    • 50
    • 9
    • 8
    • 7
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    Human
    Host
    • 44
    • 6
    Rabbit
    Clonality
    • 46
    • 4
    Polyclonal
    Conjugate
    • 22
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MED7 antibody is un-conjugated
    Application
    • 45
    • 23
    • 14
    • 12
    • 12
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Zebrafish
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CRSP9
    Isotype
    IgG
    Top Product
    Discover our top product MED7 Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    MED7 (Mediator Complex Subunit 7 (MED7))
    Alternative Name
    CRSP9 (MED7 Products)
    Synonyms
    ARC34 antibody, CRSP33 antibody, CRSP9 antibody, 1110063B05Rik antibody, Crsp33 antibody, Crsp9 antibody, crsp9 antibody, wu:fd99d12 antibody, zgc:56241 antibody, crsp9-A antibody, med7-a antibody, mediator complex subunit 7 antibody, mediator complex subunit 7 L homeolog antibody, mediator complex subunit antibody, mediator complex subunit Med7 antibody, MED7 antibody, Med7 antibody, med7 antibody, med7.L antibody
    Background

    Synonyms: Cofactor required for Sp1 transcriptional activation subunit 9, CRSP complex subunit 9, CRSP33, hMED7, MED7, MED7_HUMAN, Mediator complex subunit 7, Mediator of RNA polymerase II transcription subunit 7, MGC12284, RNA polymerase transcriptional regulation mediator subunit 7 homolog, Transcriptional coactivator CRSP33, Activator recruited cofactor 34 kDa component, Activator-recruited cofactor 34 kDa component, ARC34.

    Background: In mammalian cells, transcription is regulated in part by high molecular weight coactivating complexes that mediate signals between transcriptional activators and RNA polymerase (1). These complexes include the SMCC (SRB and MED protein cofactor complex), which consists of various subunits that share homology with several components of the yeast transcriptional mediator complexes, and including the human proteins Srb7, Med6 (also designated DRIP33) and Med7 (also designated DRIP34) (2,3). SMCC associates with the RNAPII (RNA polymerase II) holoenzyme through Srb7 and, in turn, enhances gene-specific activation or repression induced by DNA-binding transcription factors (4). Med6 and Med7, as well as other components of SMCC, associate with coactivator proteins from the TRAP (thyroid hormone receptor-activating protein) complex and DRIP (for vitamin D receptor interacting protein) complex to facilitate steroid receptor dependent transcriptional activation (4,5). Additionally, SMCC associates with PC4 (positive cofactor 4) to repress basal transcription independent of RNAPII activity (6).

    Gene ID
    9443
    Pathways
    Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
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