Syncoilin antibody

Catalog No. ABIN1386269

The Rabbit Polyclonal anti-Syncoilin antibody is suitable to detect Syncoilin in samples from Human. It has been validated for WB, IHC (p), ICC, IF and IHC (fro).

Quick Overview for Syncoilin antibody (ABIN1386269)

Target: Syncoilin (Sync)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Syncoilin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Syncoilin Antibody

Purpose: SYNC Polyclonal Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SYNC/Syncoilin

Isotype: IgG

Application Details

Application Notes: WB(1:500-2000),

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Syncoilin

Target: Syncoilin (Sync)

Alternative Name: SYNC

Background:

Synonyms: Intermediate filament protein syncoilin, SYNC, SYNC1, SYNCI_HUMAN, Syncoilin, Syncoilin intermediate filament 1, Syncoilin-1.

Background: Syncoilin (SYNC) is a 483 amino acid member of the intermediate filament family. Localized to the perinuclear region of cytoplasm, Syncoilin interacts with Alpha-Dystrobrevin and Desmin. Syncoilin links the dystrophin associated protein complex (DAPC) to desmin filaments in muscle, and is therefore found at high levels in cardiac and skeletal muscle. Syncoilin is upregulated at the sarcolemma in individuals with various forms of neuromuscular disease. The gene that encodes Syncoilin maps to human chromosome 1, which is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1.