FAM63A antibody (AA 151-250)

Catalog No. ABIN1386368

Product Details anti-FAM63A Antibody

Target: FAM63A (Family with Sequence Similarity 63, Member A (FAM63A))

Binding Specificity: AA 151-250

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAM63A antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FAM63A

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for FAM63A

Target: FAM63A (Family with Sequence Similarity 63, Member A (FAM63A))

Alternative Name: FAM63A (FAM63A Products)

Synonyms: RP11-316M1.5 antibody, 1810005H09Rik antibody, 4930504E06Rik antibody, AA562754 antibody, AA960384 antibody, AW561904 antibody, cI-40 antibody, mKIAA1390 antibody, ni antibody, si:ch211-210h11.5 antibody, MINDY lysine 48 deubiquitinase 1 antibody, MINDY1 antibody, Mindy1 antibody, mindy1 antibody

Background:

Synonyms: FA63A_HUMAN, FAM 63A, FAM63A, Family with sequence similarity 63 member A, FLJ11280, FLJ43504, Hypothetical protein LOC55793, KIAA1390, Protein FAM63A.

Background: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The FAM63A gene product has been provisionally designated FAM63A pending further characterization.

Gene ID: 55793