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ZFPM2 antibody (AA 701-800)

ZFPM2 Reactivity: Human ELISA, ICC, IF (cc), IF (p), IHC (fro), IHC (p), WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1386622
$384.62
Plus shipping costs $45.00
100 μL
Shipping to: United States
Delivery in 4 to 6 Business Days
  • Target See all ZFPM2 Antibodies
    ZFPM2 (Zinc Finger Protein, FOG Family Member 2 (ZFPM2))
    Binding Specificity
    • 10
    • 10
    • 7
    • 2
    • 1
    • 1
    AA 701-800
    Reactivity
    • 29
    • 11
    • 1
    Human
    Host
    • 30
    Rabbit
    Clonality
    • 30
    Polyclonal
    Conjugate
    • 11
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ZFPM2 antibody is un-conjugated
    Application
    ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human FOG2
    Isotype
    IgG
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    ZFPM2 (Zinc Finger Protein, FOG Family Member 2 (ZFPM2))
    Alternative Name
    FOG2 (ZFPM2 Products)
    Synonyms
    B330005D23Rik antibody, FOG-2 antibody, FOG2 antibody, DIH3 antibody, ZC2HC11B antibody, ZNF89B antibody, hFOG-2 antibody, FOG-A antibody, fog2a antibody, zgc:152696 antibody, zinc finger protein, multitype 2 antibody, zinc finger protein, FOG family member 2 antibody, zinc finger protein, FOG family member 2a antibody, Zfpm2 antibody, ZFPM2 antibody, zfpm2a antibody
    Background

    The FOG family of transcriptional cofactors, including FOG (friend of GATA-1) and FOG-2, are zinc finger proteins that interact with the GATA family of transcriptional regulators. FOG/GATA-1 complexes are required for erythroid and megakaryocyte maturation, and they promote differentiation during embryonic development. These complexes involve the association between multiple zinc fingers on the FOG proteins and the N-terminal zinc finger of GATA proteins. While FOG cooperatively regulates GATA-1 induced transcription, FOG-2 is able to both positively and negatively influence GATA mediated transcription. FOG-2 is predominantly expressed in heart, neurons and gonads, and it preferentially participates in the regulation of GATA-3, GATA-4 and GATA-6. In cardiomyocytes and fibroblasts, FOG-2 inhibits GATA-4 transcriptional activity, yet FOG-2 restores GATA-1 mediated transcription in erythroid cultures deficient in FOG, suggesting that the observed effects of FOG-2 are context specific and vary between cellular systems.

    Subcellular location: Nucleus

    Synonyms: FOG-2, FOG2_HUMAN, Friend of GATA 2, Friend of GATA protein 2, Friend of GATA2 , hFOG-2 , ZFPM2, Zinc finger protein 89B, Zinc finger protein M2, Zinc finger protein multitype 2 , Zinc finger protein ZFPM2.

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