ACCN4 antibody (AA 451-550)

Catalog No. ABIN1386698

The Rabbit Polyclonal anti-ACCN4 antibody has been validated for ELISA, IF (cc), IF (p), IHC (p), IHC (fro) and ICC. It is suitable to detect ACCN4 in samples from Human.

Quick Overview for ACCN4 antibody (AA 451-550) (ABIN1386698)

Target: ACCN4 (Amiloride-Sensitive Cation Channel 4, Pituitary (ACCN4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACCN4 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Product Details anti-ACCN4 Antibody

Binding Specificity: AA 451-550

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ACCN4/ASIC4

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for ACCN4

Target: ACCN4 (Amiloride-Sensitive Cation Channel 4, Pituitary (ACCN4))

Alternative Name: ACCN4

Background:

Synonyms: Accn4, ACCN4_HUMAN, Acid sensing proton gated ion channel family member 4, Acid sensing ion channel 4, Acid-sensing ion channel 4, Amiloride sensitive cation channel 4, Amiloride sensitive cation channel 4 pituitary, Amiloride sensitive cation channel family member 4 pituitary, Amiloride-sensitive cation channel 4, Amiloride-sensitive cation channel 4, ASIC4, BNAC4, Brain sodium channel 4, pituitary.

Background: This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC. [provided by RefSeq, Feb 2012].