ZNF281 antibody (AA 802-895)

Catalog No. ABIN1386745

This Rabbit Polyclonal antibody specifically detects ZNF281 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for ZNF281 antibody (AA 802-895) (ABIN1386745)

Target: ZNF281 (Zinc Finger Protein 281 (ZNF281))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZNF281 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ZNF281 Antibody

Binding Specificity: AA 802-895

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Cow,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ZNF281

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for ZNF281

Target: ZNF281 (Zinc Finger Protein 281 (ZNF281))

Alternative Name: ZNF281

Background:

Synonyms: Zfp281, GC box binding zinc finger protein 1, GC-box-binding zinc finger protein 1, GZP1, Transcription factor ZBP-99, ZBP 99, ZBP99, zfp281, Zinc finger DNA binding protein 99, Zinc finger DNA-binding protein 99, Zinc Finger Protein 281, ZN281_HUMAN, ZNF281, ZNP 99, ZNP 99 transcription factor, ZNP99.

Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF281, also known as GC-box-binding zinc finger protein 1, ZBP-99 or ZNP-99 (zinc finger DNA-binding protein 99), is a zinc finger protein that belongs to the Kr_ppel C2H2-type zinc finger protein family. It is expressed ubiquitously at low levels with predominant expression in kidney, liver, lymphocytes and placenta. ZNF281 localizes to the nucleus and contains four C2H2-type zinc fingers. ZNF281 plays a role in repressing the transcription of a variety of genes including Gastrin and ODC (ornithine decarboxylase). In particular, ZNF281 functions by binding to the G-rich box in the enhancer region of the gene. Upon DNA damage, ZNF281 may become phosphorylated by Atm or ATR.

Gene ID: 23528

Pathways: Embryonic Body Morphogenesis