ZNF281 antibody (AA 416-450)

Catalog No. ABIN6242706

Product Details anti-ZNF281 Antibody

Target: ZNF281 (Zinc Finger Protein 281 (ZNF281))

Binding Specificity: AA 416-450

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZNF281 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ZNF281 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 416-450 amino acids from the Central region of human ZNF281.

Clone: RB51562

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for ZNF281

Target: ZNF281 (Zinc Finger Protein 281 (ZNF281))

Alternative Name: ZNF281 (ZNF281 Products)

Synonyms: ZNF281 antibody, zbp-99 antibody, znp-99 antibody, ZBP-99 antibody, ZNP-99 antibody, Znf281 antibody, zinc finger protein 281 antibody, ZNF281 antibody, znf281 antibody, Zfp281 antibody

Background: Transcription repressor that plays a role in regulation of embryonic stem cells (ESCs) differentiation. Required for ESCs differentiation and acts by mediating autorepression of NANOG in ESCs: binds to the NANOG promoter and promotes association of NANOG protein to its own promoter and recruits the NuRD complex, which deacetylates histones. Not required for establishement and maintenance of ESCs (By similarity). Represses the transcription of a number of genes including GAST, ODC1 and VIM. Binds to the G- rich box in the enhancer region of these genes.

Molecular Weight: 96915

UniProt: Q9Y2X9

Pathways: Embryonic Body Morphogenesis