RAB40A antibody (AA 171-277)

Catalog No. ABIN1386817

Product Details anti-RAB40A Antibody

Target: RAB40A (RAB40A, Member RAS Oncogene Family (RAB40A))

Binding Specificity: AA 171-277

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAB40A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RAB40A

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for RAB40A

Target: RAB40A (RAB40A, Member RAS Oncogene Family (RAB40A))

Alternative Name: RAB40A (RAB40A Products)

Synonyms: RAR2 antibody, RAR2A antibody, RAB40A, member RAS oncogene family antibody, RAB40A antibody

Background:

Synonyms: Protein Rar 2, RAB40A, member RAS oncogene family, Rar 2, RAR2A, Ras related protein Rab 40A, SOCS box containing protein RAR2A, RB40A_HUMAN.

Background: The Ras-related superfamily of guanine nucleotide binding proteins includes the R-Ras, Rap, Ral/Rec and Rho/Rab subfamilies all of which are thought to play an important role in either endocytosis or in biosynthetic protein transport. The process of transporting newly synthesized proteins from the endoplasmic reticulum (ER) to various stacks of the Golgi complex and to secretory vesicles involves the movement of carrier vesicles and requires Rab protein function. Rab proteins are also an integral part of endocytic pathways. Rab 40A, Rab 40B and Rab 40C each contain one SOCS box domain and are members of the Rab subfamily of GTPases. Localized to the cytoplasmic side of the cell membrane, Rab 40A, Rab 40B and Rab 40C are thought to function as substrate-recognition components of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex that functions to mediate the degradation of target proteins.

Gene ID: 142684