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PDZD4 antibody

PDZD4 Reactivity: Human, Mouse, Rat WB, IF (p), IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1386897
  • Target See all PDZD4 products
    PDZD4 (PDZ Domain Containing 4 (PDZD4))
    Reactivity
    • 32
    • 24
    • 16
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 32
    Rabbit
    Clonality
    • 32
    Polyclonal
    Conjugate
    • 8
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PDZD4 antibody is un-conjugated
    Application
    • 32
    • 12
    • 12
    • 2
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human PDZK4
    Isotype
    IgG
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    PDZD4 (PDZ Domain Containing 4 (PDZD4))
    Alternative Name
    PDZK4 (PDZD4 Products)
    Synonyms
    LU1 antibody, PDZK4 antibody, PDZRN4L antibody, B230341P03 antibody, D130075J17Rik antibody, Kiaa1444-hp antibody, Pdzk4 antibody, Pdzrnk4l antibody, Xlu antibody, PDZ domain containing 4 antibody, PDZD4 antibody, Pdzd4 antibody
    Background

    Synonyms: FERM and PDZ domain containing protein 2, PDZ domain containing protein 4, PDZ domain containing protein 5C, PDZ domain containing 4 PDZD5C, PDZK4, PDZK5C,FRPD2_HUMAN.

    Background: PDZK4, also known as PDZRN4L (PDZ domain-containing RING finger protein 4-like protein) or LU1, is a 769 amino acid coiled-coil protein that contains one PDZ (DHR) domain. Encoded by a gene that maps to human chromosome Xq28, PDZK4 is conserved in dog, cow, mouse, rat and zebrafish. PDZK4 localizes to cytoplasm and is expressed specifically in adult and fetal brain. PDZK4 functions as an oncogene and is up-regulated in synovial carcinomas. Treatment of synovial sarcoma cells with small interfering RNA (siRNA) inhibits PDZK4 expression, resulting in tumor-cell growth suppression, suggesting that inappropriate expression of PDZK4 may play a role synovial sarcoma cell proliferation.The exact function of FRMPD2 is unknown. The protein contains a FERM domain: such structures are often involved in signal transduction pathways. Alternatively spliced transcript variants encoding different isoforms have been identified.

    Gene ID
    143162
    UniProt
    Q68DX3
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