ANKS6 antibody

Catalog No. ABIN1386931

Product Details anti-ANKS6 Antibody

Target: ANKS6 (Ankyrin Repeat and Sterile alpha Motif Domain Containing 6 (ANKS6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANKS6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ANKS6

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for ANKS6

Target: ANKS6 (Ankyrin Repeat and Sterile alpha Motif Domain Containing 6 (ANKS6))

Alternative Name: ANKS6 (ANKS6 Products)

Synonyms: ANKRD14 antibody, PKDR1 antibody, SAMD6 antibody, 2210417J20Rik antibody, Ankrd14 antibody, Gm635 antibody, SamCystin antibody, Samd6 antibody, Pkdr1 antibody, ankyrin repeat and sterile alpha motif domain containing 6 antibody, ANKS6 antibody, Anks6 antibody

Background:

Synonyms: ANKRD14, Anks6, ANKS6_HUMAN, ankyrin repeat and SAM domain containing protein 6, Ankyrin repeat and SAM domain-containing protein 6, ankyrin repeat domain 14, ankyrin repeat domain containing protein 14, Ankyrin repeat domain-containing protein 14, SAM domain containing protein 6, SAM domain-containing protein 6, SamCystin, SAMD6, sterile alpha mot domain containing 6, sterile alpha mot domain containing protein 6, Sterile alpha mot domain-containing protein 6.

Background: ANKS6, also known as ankyrin repeat domain-containing protein 14, SAMD6 (sterile alpha motif domain-containing protein 6), SamCystin or PKDR1, is an 871 amino acid phosphoprotein that contains eleven ANK repeats, one SAM domain and exists as three alternatively spliced isoforms. Encoded by a gene that maps to human chromosome 9q22.33, ANKS6 is necessary for renal function and is linked to renal cyst formation in polycystic kidney disease. ANKS6 interacts with BICC1, another protein linked to polycystic kidney disease, and both co-localize to the same cell region. ANKS6 is involved in proteinprotein interactions with both itself as well as BICC1, and both proteins function in a molecular pathway that is linked to cystogenesis. ANKS6 may also be associated with dental anomolies.

Gene ID: 203286