ATAD2 antibody (AA 1025-1063)

Catalog No. ABIN1386935

The Rabbit Polyclonal anti-ATAD2 antibody is suitable to detect ATAD2 in samples from Human. It has been validated for IF, IHC (p) and IHC (fro).

Quick Overview for ATAD2 antibody (AA 1025-1063) (ABIN1386935)

Target: ATAD2 (ATPase Family, AAA Domain Containing 2 (ATAD2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATAD2 antibody is un-conjugated

Application: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-ATAD2 Antibody

Binding Specificity: AA 1025-1063

Purpose: ATAD2 Polyclonal Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ATAD2

Isotype: IgG

Application Details

Application Notes: IHC-P(IHC-P=1:100-500), IHC-F(IHC-F=1:100-500), IF(IF=1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for ATAD2

Target: ATAD2 (ATPase Family, AAA Domain Containing 2 (ATAD2))

Alternative Name: ATAD2

Background:

Synonyms: ANCCA, CT137, PRO2000, ATPase family AAA domain-containing protein 2, AAA nuclear coregulator cancer-associated protein, ATAD2, L16

Background: May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells.

Gene ID: 29028

UniProt: Q6PL18