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TMIGD1 antibody (AA 160-200)

TMIGD1 Reactivity: Human, Mouse, Rat WB, IHC (p), IF (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1387070
  • Target See all TMIGD1 Antibodies
    TMIGD1 (Transmembrane and Immunoglobulin Domain Containing 1 (TMIGD1))
    Binding Specificity
    • 1
    • 1
    AA 160-200
    Reactivity
    Human, Mouse, Rat
    Host
    • 1
    • 1
    Rabbit
    Clonality
    • 1
    • 1
    Polyclonal
    Conjugate
    • 2
    This TMIGD1 antibody is un-conjugated
    Application
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human TMIGD1
    Isotype
    IgG
    Top Product
    Discover our top product TMIGD1 Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    TMIGD1 (Transmembrane and Immunoglobulin Domain Containing 1 (TMIGD1))
    Alternative Name
    TMIGD1 (TMIGD1 Products)
    Synonyms
    RGD1307444 antibody, Tmigd antibody, TMIGD antibody, UNQ9372 antibody, 2010002A20Rik antibody, transmembrane and immunoglobulin domain containing 1 antibody, Tmigd1 antibody, TMIGD1 antibody
    Background

    Synonyms: TMIGD, UNQ9372, Transmembrane and immunoglobulin domain-containing protein 1, TMIGD1, UNQ9372/PRO34164

    Background: Chromosome 17 makes up over 2.5 % of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dub? syndrome and Canavan disease are also associated with chromosome 17.

    Gene ID
    388364
    UniProt
    Q6UXZ0
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