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JMJD7 antibody

JMJD7 Reactivity: Human, Mouse, Rat WB, IF (p), IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1387084
  • Target See all JMJD7 Antibodies
    JMJD7 (Jumonji Domain Containing 7 (JMJD7))
    Reactivity
    • 20
    • 18
    • 18
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 20
    Rabbit
    Clonality
    • 20
    Polyclonal
    Conjugate
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This JMJD7 antibody is un-conjugated
    Application
    • 20
    • 12
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human JMJD7
    Isotype
    IgG
    Top Product
    Discover our top product JMJD7 Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    JMJD7 (Jumonji Domain Containing 7 (JMJD7))
    Alternative Name
    JMJD7 (JMJD7 Products)
    Synonyms
    jumonji domain containing 7 antibody, JMJD7 antibody, Jmjd7 antibody
    Background

    Synonyms: JmjC domain-containing protein 7, JMJD7, JMJD7_HUMAN, Jumonji domain containing 7, Jumonji domain-containing protein 7.

    Background: A crucial regulator of chromatin dynamics and DNA transcription is the covalent modification and methylation of histones. Generally, methylation of certain lysine residues on Histone H3 and Histone H4 can be associated with transcriptionally active or inactive chromatin. This regulation has profound effects on the expression of genes and is part of an epigenetic memory network that determines cell fate. JMJD7 (Jumonji domain-containing protein 7) is a member of a family of JMJC domain-containing histone demethylases that are directly involved in removing methyl residues from distinct and unique lysine residues. These actions are implicated in gene expression and the regulation of cell senescence. JMJC domain-containing histone demethylases are also likely involved in development via their ability to regulate gene expression. JMJD7 contains one JMJC domain and was originally thought to be an alternatively spliced isoform of PLA2G4B.

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