RPUSD2 antibody

Catalog No. ABIN1387113

The Rabbit Polyclonal anti-RPUSD2 antibody (ABIN1387113) specifically detects RPUSD2 in WB, IF (p) and IHC (p). The antibody is reactive with Human samples.

Quick Overview for RPUSD2 antibody (ABIN1387113)

Target: RPUSD2 (RNA Pseudouridylate Synthase Domain Containing 2 (RPUSD2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPUSD2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-RPUSD2 Antibody

Purpose: RPUSD2 Polyclonal Antibody

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow,Sheep

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RPUSD2

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000), IHC-P(1:200-400), IF(IHC-P)(1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for RPUSD2

Target: RPUSD2 (RNA Pseudouridylate Synthase Domain Containing 2 (RPUSD2))

Alternative Name: RPUSD2

Background:

Synonyms: C15orf19, C18B11, C18B11 homolog, RNA pseudouridylate synthase domain containing 2, RNA pseudouridylate synthase domain containing protein 2, RNA pseudouridylate synthase domain-containing protein 2, RPUSD 2, RPUSD-2, RUSD2_HUMAN.

Background: RPUSD2, is a 545 amino acid member of the pseudouridine synthase rluA family and is encoded by a gene that is located on chromosome 15. Encoding more than 700 genes, chromosome 15 is made up of approximately 106 million base pairs and is about 3 % of the human genome. Angelman and Prader-Willi syndromes are associated with loss of function or deletion of genes in the 15q11-q13 region. In the case of Angelman syndrome, this loss is due to inactivity of the maternal 15q11-q13 encoded UBE3A gene in the brain by either chromosomal deletion or mutation. In cases of Prader-Willi syndrome, there is a partial or complete deletion of this region from the paternal copy of chromosome 15. Tay-Sachs disease is a lethal disorder associated with mutations of the HEXA gene, which is encoded by chromosome 15. Marfan syndrome is associated with chromosome 15 through the FBN1 gene.

Gene ID: 27079