CCSAP antibody

Catalog No. ABIN1387174

Product Details anti-CCSAP Antibody

Target: CCSAP (Centriole, Cilia and Spindle Associated Protein (CCSAP))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCSAP antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C1orf96

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for CCSAP

Target: CCSAP (Centriole, Cilia and Spindle Associated Protein (CCSAP))

Alternative Name: C1orf96 (CCSAP Products)

Synonyms: C1orf96 antibody, CSAP antibody, 1700054N08Rik antibody, AI853424 antibody, centriole, cilia and spindle associated protein antibody, CCSAP antibody, Ccsap antibody

Background:

Synonyms: C1orf96, FLJ37296, FLJ41471, Uncharacterized protein C1orf96, CCSAP_HUMAN, Centriole, cilia and spindle-associated protein, CCSAP, CSAP, RP4-803J11.3.

Background: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf96 gene product has been provisionally designated C1orf96 pending further characterization.

Gene ID: 126731