WIPF2 antibody

Catalog No. ABIN1387209

The Rabbit Polyclonal anti-WIPF2 antibody (ABIN1387209) specifically detects WIPF2 in WB, IHC (p), IF and IHC (fro). The antibody is reactive with Human samples.

Quick Overview for WIPF2 antibody (ABIN1387209)

Target: WIPF2 (WAS/WASL Interacting Protein Family, Member 2 (WIPF2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WIPF2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-WIPF2 Antibody

Purpose: WIPF2 Polyclonal Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human WIPF2

Isotype: IgG

Application Details

Application Notes: WB(WB=1:500-2000), IHC-P(IHC-P=1:100-500), IHC-F(IHC-F=1:100-500), IF(IF=1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for WIPF2

Target: WIPF2 (WAS/WASL Interacting Protein Family, Member 2 (WIPF2))

Alternative Name: WIPF2

Background:

Synonyms: WAS/WASL interacting protein family member 2, WASP binding protein, WASP interacting protein related protein, WICH, WIP and CR16 homologous protein, WIP related protein, WIPF 2, WIR, WIPF2_HUMAN.

Background: WIRE, also known as WIPF2 (WAS/WASL interacting protein family, member 2) or WICH, is a 440 amino acid protein that localizes to both the cytoplasm and the cytoskeleton and contains one WH2 domain. Expressed ubiquitously with highest expression in colon, brain, lung and stomach, WIRE functions as an N-WASP-interacting protein that plays an important role in the organization and mobilization of the Actin cytoskeleton. Additionally, WIRE is involved in the formation of cell surface protrusions and may also provide a link between the cytoskeletal machinery and PDGF-B receptors. Multiple alternatively spliced isoforms of WIRE exist and are encoded by a gene that maps to human chromosome 17.

Gene ID: 147179