NIR1 antibody (AA 131-250)

Catalog No. ABIN1387251

This anti-NIR1 antibody is a Rabbit Polyclonal antibody detecting NIR1 in WB, ELISA, IHC (p), IF (cc), IF (p) and IHC (fro). Suitable for Human.

Quick Overview for NIR1 antibody (AA 131-250) (ABIN1387251)

Target: NIR1 (PITPNM3) (PITPNM Family Member 3 (PITPNM3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NIR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-NIR1 Antibody

Binding Specificity: AA 131-250

Predicted Reactivity: Human,Mouse,Rat,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NIR1/RDGBA3

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for NIR1

Target: NIR1 (PITPNM3) (PITPNM Family Member 3 (PITPNM3))

Alternative Name: NIR1

Background:

Synonyms: membrane-associated 3, CORD5, Membrane associated phosphatidylinositol transfer protein 3, Membrane-associated phosphatidylinositol transfer protein 3, NIR 1, NIR-1, NIR1, Phosphatidylinositol transfer protein, Phosphatidylinositol transfer protein, membrane-associated 3, PITM3_HUMAN, PITPnm 3, PITPNM, PITPNM family member 3, Pitpnm3, PYK2 N terminal domain interacting receptor 1, PYK2 N-terminal domain-interacting receptor 1, RDGBA3, retinal degeneration B alpha 3.

Background: Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes (in vitro) (By similarity). Binds calcium ions.Involvement in disease:Defects in PITPNM3 are the cause of cone-rod dystrophy type 5 (CORD5) . CORDs are inherited retinal dystrophies belonging to the group of pigmentary retinopathies. CORDs are characterized by retinal pigment deposits visible on fundus examination, predominantly in the macular region, and initial loss of cone photoreceptors followed by rod degeneration.

Gene ID: 83394