HES6 antibody (AA 1-80)

Catalog No. ABIN1387271

Product Details anti-HES6 Antibody

Target: HES6 (Hairy and Enhancer of Split 6 (HES6))

Binding Specificity: AA 1-80

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HES6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Cow,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HES6

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for HES6

Target: HES6 (Hairy and Enhancer of Split 6 (HES6))

Alternative Name: HES6 (HES6 Products)

Synonyms: YF-30 antibody, her13.2 antibody, AI326893 antibody, bHLHb41 antibody, HES-6 antibody, bHLHc23 antibody, hes family bHLH transcription factor 6 antibody, hairy and enhancer of split 6 antibody, hes6 antibody, Hes6 antibody, HES6 antibody

Background:

Synonyms: HES-6, bHLHb41, bHLHc23, C-HAIRY1, Transcription cofactor HES-6, Class B basic helix-loop-helix protein 41, Hairy and enhancer of split 6, HES6

Background: Does not bind DNA itself but suppresses both HES1-mediated N box-dependent transcriptional repression and binding of HES1 to E box sequences. Also suppresses HES1-mediated inhibition of the heterodimer formed by ASCL1/MASH1 and TCF3/E47, allowing ASCL1 and TCF3 to up-regulate transcription in its presence. Promotes cell differentiation (By similarity).

Gene ID: 55502

UniProt: Q96HZ4