ZIC2 antibody (AA 201-300)

Catalog No. ABIN1387295

The Rabbit Polyclonal anti-ZIC2 antibody is suitable to detect ZIC2 in samples from Human. It has been validated for WB, IF (cc), IF (p), IHC (p) and IHC (fro).

Quick Overview for ZIC2 antibody (AA 201-300) (ABIN1387295)

Target: ZIC2

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZIC2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-ZIC2 Antibody

Binding Specificity: AA 201-300

Purpose: Zic2 Polyclonal Antibody

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Cow,Sheep,Pig,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Zic2

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000),

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for ZIC2

Target: ZIC2

Alternative Name: Zic2

Background:

Synonyms: HPE 5, HPE5, Odd paired homolog Drosophila, Zic 2, Zic family member 2 odd paired Drosophila homolog, Zic family member 2, ZIC2, ZIC2_HUMAN, Zinc finger protein of the cerebellum 2, Zinc finger protein ZIC 2, Zinc finger protein Zic2.

Background: Zic2 is a C2H2 zinc finger transcription factor that influences forebrain development. Zic2 is a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Zic2 transcript is abundant in the dorsal neural tube/spinal cord, and in the hindbrain. A polyhistidine tract polymorphism in this gene may be associated with increased risk of neural tube defects. This gene is closely linked to a gene encoding zinc finger protein of the cerebellum 5, a related family member on chromosome 13.

Pathways: Tube Formation