Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

HELT antibody (AA 156-220)

HELT Reactivity: Human WB, ELISA, IHC (p), IF (p), IHC (fro), ICC, IF (cc) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1387384
  • Target See all HELT Antibodies
    HELT (Helt BHLH Transcription Factor (HELT))
    Binding Specificity
    • 8
    • 6
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    AA 156-220
    Reactivity
    • 27
    • 20
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 27
    Rabbit
    Clonality
    • 27
    Polyclonal
    Conjugate
    • 10
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HELT antibody is un-conjugated
    Application
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc))
    Predicted Reactivity
    Human,Mouse,Rat,Cow,Sheep,Horse,Rabbit,Zebrafish
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human HELT
    Isotype
    IgG
    Top Product
    Discover our top product HELT Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    HELT (Helt BHLH Transcription Factor (HELT))
    Alternative Name
    HELT (HELT Products)
    Synonyms
    HCM1228 antibody, HESL antibody, Mgn antibody, bHLHb44 antibody, A830086M02 antibody, Hesl antibody, megane antibody, Helt-ps1 antibody, RGD1564073 antibody, zgc:109704 antibody, helt bHLH transcription factor antibody, HELT antibody, Helt antibody, helt antibody
    Background

    Synonyms: Hairy and enhancer of split-related protein HELT, HCM1228, HELT, HELT_HUMAN, HES like , HES/HEY like transcription factor, HES/HEY-like transcription factor, HESL, Heslike , Hey like transcription factor, Hey like transcription factor zebrafish, Hey like transcriptional repressor, Megane bHLH factor, Mgn.

    Background: The Drosophila hairy and Enhancer of split genes encode basic helix-loop-helix (bHLH) transcriptional repressors that function in the Notch signaling pathway and control segmentation and neural development during embryogenesis. The Notch signaling pathway is thought to maintain stem cells through transcriptional activation of HES/HEY family members to repress tissue-specific transcription factors. HESL (HES-like), also known as Mgn or HELT (HES/HEY-like transcription factor), is a 327 amino acid nuclear protein belonging to the HEY family. Containing a basic helix-loop-helix (bHLH) domain and an Orange domain, HESL self-associates and interacts with HES5 and HRT2. HESL is considered a transcriptional repressor that binds to the canonical E box sequence 5'-CACGCG-3'. HESL exists as two isoforms produced by alternative splicing events.

    Pathways
    Feeding Behaviour
You are here:
Support