FCHSD1 antibody (AA 151-250)

Catalog No. ABIN1387421

The Rabbit Polyclonal anti-FCHSD1 antibody is suitable to detect FCHSD1 in samples from Human. It has been validated for IF (cc), IF (p), IHC (p) and IHC (fro).

Quick Overview for FCHSD1 antibody (AA 151-250) (ABIN1387421)

Target: FCHSD1 (Similar To FCH and Double SH3 Domains 1 (FCHSD1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FCHSD1 antibody is un-conjugated

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-FCHSD1 Antibody

Binding Specificity: AA 151-250

Purpose: FCHSD1 Polyclonal Antibody

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FCHSD1

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for FCHSD1

Target: FCHSD1 (Similar To FCH and Double SH3 Domains 1 (FCHSD1))

Alternative Name: FCHSD1

Background:

Synonyms: FCH and double SH3 domains 1, FCH and double SH3 domains protein 1, FCHSD 1, FCHSD1, FCSD1_HUMAN, FLJ00007, Nervous wreck homolog 2, NWK 2, NWK2.

Background: FCHSD1 is a 690 amino acid protein that contains one FCH domain and two SH3 domains. FCHSD1 exists as three isoforms as a result of alternative splicing events. The gene encoding FCHSD1 maps to chromosome 5, which is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.

Gene ID: 89848