PAPSS1 antibody

Catalog No. ABIN1387424

The Rabbit Polyclonal anti-PAPSS1 antibody is suitable to detect PAPSS1 in samples from Human, Mouse and Rat. It has been validated for IHC (p) and IF (p).

Quick Overview for PAPSS1 antibody (ABIN1387424)

Target: PAPSS1 (3'-phosphoadenosine 5'-phosphosulfate Synthase 1 (PAPSS1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAPSS1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-PAPSS1 Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PAPSS1

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for PAPSS1

Target: PAPSS1 (3'-phosphoadenosine 5'-phosphosulfate Synthase 1 (PAPSS1))

Alternative Name: PAPSS1

Background:

Synonyms: Adenylyl-sulfate kinase, Adenylylsulfate 3''-phosphotransferase, APS kinase, ATP-sulfurylase, ATPSK 1, ATPSK1, Bunctional 3' phosphoadenosine 5' phosphosulfate synthetase 1, PAPS synthase 1, PAPS synthetase 1, PAPS1_HUMAN, PAPSS 1, PAPSS, PAPSS1, SAT, SK 1, SK1, Sulfate adenylate transferase, Sulfurylase kinase 1, 3 prime phosphoadenosine 5 prime phosphosulfate synthase 1, 3' phosphoadenosine 5' phosphosulfate synthase 1, 3''-phosphoadenosine-5''-phosphosulfate synthase, Adenosine-5''-phosphosulfate 3''-phosphotransferase.

Background: Three-prime-phosphoadenosine 5-prime-phosphosulfate (PAPS) is the sulfate donor cosubstrate for all sulfotransferase (SULT) enzymes (Xu et al., 2000 [PubMed 10679223]). SULTs catalyze the sulfate conjugation of many endogenous and exogenous compounds, including drugs and other xenobiotics. In humans, PAPS is synthesized from adenosine 5-prime triphosphate (ATP) and inorganic sulfate by 2 isoforms, PAPSS1 and PAPSS2 (MIM 603005).[supplied by OMIM, Mar 2008].

Gene ID: 9061

Pathways: Glycosaminoglycan Metabolic Process, Ribonucleoside Biosynthetic Process