PAPSS1 antibody (AA 190-260)

Catalog No. ABIN6145215

The Rabbit Polyclonal anti-PAPSS1 antibody is suitable to detect PAPSS1 in samples from Human. It has been validated for WB.

Quick Overview for PAPSS1 antibody (AA 190-260) (ABIN6145215)

Target: PAPSS1 (3'-phosphoadenosine 5'-phosphosulfate Synthase 1 (PAPSS1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAPSS1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PAPSS1 Antibody

Binding Specificity: AA 190-260

Sequence: SEYEKPEAPE LVLKTDSCDV NDCVQQVVEL LQERDIVPVD ASYEVKELYV PENKLHLAKT DAETLPALKI N

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 190-260 of human PAPSS1 (NP_005434.4).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PAPSS1

Target: PAPSS1 (3'-phosphoadenosine 5'-phosphosulfate Synthase 1 (PAPSS1))

Alternative Name: PAPSS1

Background: Three-prime-phosphoadenosine 5-prime-phosphosulfate (PAPS) is the sulfate donor cosubstrate for all sulfotransferase (SULT) enzymes (Xu et al., 2000 [PubMed 10679223]). SULTs catalyze the sulfate conjugation of many endogenous and exogenous compounds, including drugs and other xenobiotics. In humans, PAPS is synthesized from adenosine 5-prime triphosphate (ATP) and inorganic sulfate by 2 isoforms, PAPSS1 and PAPSS2 (MIM 603005).[supplied by OMIM, Mar 2008],PAPSS1,ATPSK1,PAPSS,SK1,PAPSS1

Molecular Weight: 70 kDa

Gene ID: 9061

UniProt: O43252

Pathways: Glycosaminoglycan Metabolic Process, Ribonucleoside Biosynthetic Process