TRIP13 antibody (AA 201-300)

Catalog No. ABIN1387429

This Rabbit Polyclonal antibody specifically detects TRIP13 in WB, ELISA, IHC (p), IF (cc), IF (p), ICC and IHC (fro). It exhibits reactivity toward Mouse.

Quick Overview for TRIP13 antibody (AA 201-300) (ABIN1387429)

Target: TRIP13 (Thyroid Hormone Receptor Interactor 13 (TRIP13))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIP13 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-TRIP13 Antibody

Binding Specificity: AA 201-300

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TRIP13/16E1BP

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for TRIP13

Target: TRIP13 (Thyroid Hormone Receptor Interactor 13 (TRIP13))

Alternative Name: TRIP13/16E1BP

Background:

Synonyms: 16E1-BP, 16E1BP, Homo sapiens HPV16 E1 protein binding protein mRNA complete cds, HPV16 E1 protein binding protein, HPV16 E1 protein-binding protein, Human papillomavirus type 16 E1 protein binding protein, Human papillomavirus type 16 E1 protein-binding protein, Pachytene checkpoint protein 2 homolog, PCH2, Thyroid hormone receptor interactor 13, Thyroid receptor interacting protein 13, Thyroid receptor-interacting protein 13, TR-interacting protein 13, TRIP-13, Trip13, TRP13_HUMAN.

Background: Thyroid hormone receptors (TRs) are transcription factors that regulate the expression of specific genes in a hormone-dependent manner. TRIP13 is a transcription factor that interacts with the ligand binding domain of the thyroid receptor (TR) as well as a variety of target genes including human papilloma virus type 16 (HPV16) E1. Unlike most TRIP proteins which function only in the presence of hormones, TRIP13 does not require the presence of thyroid hormone to interact with TR. The association of TRIP13 with (HPV16) E1 suggests that TRIP13 may have tumor suppressor gene function. TRIP13 is a 432 amino acid protein with 2 different isoforms produced by alternative splicing.

Gene ID: 9319