SAG antibody (AA 285-330)

Catalog No. ABIN1387479

The Rabbit Polyclonal anti-SAG antibody (ABIN1387479) specifically detects SAG in WB, ELISA, ICC, IHC (fro), IHC (p), IF (cc) and IF (p). The antibody is reactive with Human samples.

Quick Overview for SAG antibody (AA 285-330) (ABIN1387479)

Target: SAG (S-Antigen, Retina and Pineal Gland (Arrestin) (SAG))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SAG antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-SAG Antibody

Binding Specificity: AA 285-330

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Retinal S antigen

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for SAG

Target: SAG (S-Antigen, Retina and Pineal Gland (Arrestin) (SAG))

Alternative Name: Retinal S antigen/S-antigen

Background:

Synonyms: 48 kDa protein, Arrestin 1, Arrestin, ARRS_HUMAN, DKFZp686I1383, Retinal S antigen 48 KDa protein, Retinal S-antigen, Rod photoreceptor arrestin, RP47, S AG, S antigen, S antigen retina and pineal gland arrestin, S antigen retina and pineal gland, S arrestin, S-AG, S-arrestin, SAG.

Background: Plasmodium falciparum is a protozoan parasite that causes malaria. It exhibits considerable antigenic heterogeneity which may be a major problem in developing an effective vaccine against malaria. The S-antigen of Plasmodium falciparum is a highly diverse, heat stable protein that is located in the parasitophorous vacuole of the mature asexual intraerythrocytic parasite. The S-antigen gene consists of multiple alleles that originate from the same chromosome site. The amino acid sequence of each allele contains a large central section of tandemly arranged, nearly identical peptides that are specific to each allele. Thus, directed against the repeat region of a particular allele can be used to define the serotype of an S-antigen. Flanking the central repeat block are two short regions of non-repetitive sequence which occur in four different forms, each of which is utilized to define a single S-antigen family. Comparison of the four S-antigen families reveals t hat they differ considerably from each other with variation being most pronounced in the C-terminal-flanking region.

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling